Prices verified Jun 22 · Always confirm at the retailer before buying.
The Purilens Plus saline wins for most lens wearers — preservative-free comfort for a 3-month supply beats Boston Advance's conditioning for hard lenses.
The Verdict
Best for most people
Purilens Plus Preservative-Free Contact Lens Saline
Preservative-free, pH-balanced formula eliminates end-of-day irritation for soft lens wearers with sensitive eyes.
Pick the Boston Advance Conditioning Solution instead if
- You're on a tight budget — Purilens costs about half as much for a 3-month supply, without sacrificing eye comfort.
- You wear rigid gas permeable lenses — Boston Advance is specifically formulated to condition and disinfect hard lenses.
- You need a solution that also disinfects overnight — Boston Advance is a conditioning solution with disinfection, while Purilens is a rinse.
Purilens Plus Preservative-Free Contact Lens Saline vs Boston Advance Conditioning Solution, side by side
Purilens Plus Preservative-Free Contact Lens Saline
Pros:
- Preservative-free formula prevents irritation — 8,146 verified reviews at 4.8★
- per ounce, a 3-month supply for under $20
- pH balanced to match natural tears, reducing stinging
- Compatible with all soft and rigid gas permeable lenses
Cons (honest weight):
- Must discard within 30 days after opening — no preservatives
- Small 4 oz bottles require frequent repurchase for heavy users
- Not a disinfectant; needs a separate cleaning solution
Boston Advance Conditioning Solution
Pros:
- Exclusively for rigid gas permeable lenses — 4.6★ from 8,718 ratings
- Conditions lens surface for comfortable long-term wear
- Includes two 3.5 oz bottles for extended use
- Proven disinfection for overnight lens care
Cons (honest weight):
- Higher price per ounce versus saline alternatives
- Not suitable for soft lenses — limited to hard/gas permeable
- Contains preservatives which may irritate very sensitive eyes
Where each one wins
8 dimensions scored head-to-head. Purilens Plus takes 6; Boston Advance takes 2.
| Dimension | Purilens Plus Preservative-Free Contact Lens Saline | Boston Advance Conditioning Solution | Winner |
|---|---|---|---|
| Price per OuncePurilens costs 62% less per ounce, making it the clear value pick. | $1.66/oz | $4.38/oz | Purilens Plus |
| Preservative-FreePurilens is free of preservatives, reducing irritation for sensitive eyes. | Yes | No | Purilens Plus |
| Soft Lens CompatiblePurilens works with all soft lenses; Boston Advance is only for hard lenses. | Yes | No | Purilens Plus |
| Hard Lens CompatibleBoston Advance is purpose-built for rigid gas permeable lenses. | No | Yes | Boston Advance |
| DisinfectionBoston Advance disinfects overnight; Purilens is a saline rinse, not a disinfectant. | Rinse only | Yes | Boston Advance |
| Sensitive Eyes SuitablePurilens' preservative-free formula is ideal for allergic or sensitive eyes. | Excellent | Possible irritation | Purilens Plus |
| Customer RatingPurilens edges out in average rating, but both are highly reviewed. | 4.8★ | 4.6★ | Purilens Plus |
| Value (Reviews per $)Purilens delivers more buyer feedback per dollar spent. | 408 reviews/$ | 284 reviews/$ | Purilens Plus |
| Overall | 6 wins | 2 wins | Purilens Plus |
Price per Ounce — Purilens Wins
Purilens per ounce, while Boston Advance runs per ounce. That's a 62% premium for the conditioning formula.
If you rinse lenses daily, the Purilens three-pack gives you roughly three months of use. Boston Advance's two 3.5 oz bottles supply nightly disinfection for up to two months.
Budget-conscious users and soft lens wearers should prioritize Purilens, as the ongoing cost is significantly lower.
Preservative-Free — Purilens Wins
Purilens contains no preservatives, making it safer for sensitive eyes. Boston Advance includes preservatives to maintain sterility during storage.
Without preservatives, Purilens eliminates a common irritant that causes redness and stinging after long wear. The trade-off is a shorter 30-day shelf life once opened.
If you have dry eyes or allergies, a preservative-free rinse is worth the more frequent repurchasing.
Soft Lens Compatible — Purilens Wins
Purilens is approved for all soft contact lenses, including silicone hydrogel types. Boston Advance is not designed for soft lenses at all.
Soft lens wearers need a saline solution that doesn't interact with lens polymers. Purilens' simple formula cleans without leaving residues that can build up on soft lenses.
The vast majority of lens wearers use soft lenses, so this compatibility is a decisive advantage for Purilens.
Hard Lens Compatible — Boston Advance Wins
Boston Advance is formulated exclusively for rigid gas permeable lenses. Purilens does not provide the conditioning that hard lenses require.
RGP lenses need a solution that both disinfects and conditions the surface to maintain comfort. Boston Advance's conditioning agents help reduce friction on the eyelid during blinking.
If you wear hard lenses, Boston Advance is the clear choice to preserve lens lifespan and daily comfort.
Disinfection — Boston Advance Wins
Boston Advance kills bacteria and disinfects lenses overnight. Purilens is a simple saline rinse with no antibacterial properties.
For overnight storage, a disinfecting solution is essential to prevent eye infections. Boston Advance's formula meets FDA standards for contact lens disinfection.
If you need a complete care system, Boston Advance is the only option of the two for safe overnight use.
Sensitive Eyes Suitable — Purilens Wins
Purilens' gentle, pH-balanced saline is safe for even the most reactive eyes. Boston Advance's preservatives can cause stinging in some users.
Eye doctors often recommend preservative-free saline for patients with chronic dry eye or ocular allergies. Purilens matches the pH of natural tears, reducing that typical saline sting.
Anyone who has experienced lens irritation will appreciate Purilens' immediate comfort boost.
Customer Rating — Purilens Wins
Purilens holds a 4.8-star average from 8,146 reviews, versus Boston Advance's 4.6 stars from 8,718 reviews. Both are very well-rated.
The slightly higher rating for Purilens reflects its success at the one job that matters — reducing irritation. Boston Advance reviews praise its effectiveness for hard lens care, but some note preservative sensitivity.
Both products enjoy strong loyalty, so you can trust the feedback for your lens type.
Value (Reviews per $) — Purilens Wins
Purilens accumulates 408 verified reviews per dollar spent, almost 1.5 times Boston Advance's 284 reviews per dollar.
This ratio shows that Purilens delivers a higher volume of consumer validation relative to its price. More buyers are willing to share their experience at this price point.
Value-conscious shoppers can feel confident that Purilens is widely tested and approved.
Which should you buy?
| Your situation | Pick | Why |
|---|---|---|
| Daily soft lens wearer | Purilens Plus Preservative-Free Contact Lens Saline | Purilens soothes and rinses without irritation for all-day comfort. |
| Sensitive or dry eyes | Purilens Plus Preservative-Free Contact Lens Saline | Preservative-free, pH-balanced saline prevents stinging and redness. |
| Budget-friendly purchase | Purilens Plus Preservative-Free Contact Lens Saline | per ounce, delivering a 3-month supply for under $20. |
| RGP lens user | Boston Advance Conditioning Solution | Boston Advance conditions and disinfects gas permeable lenses. |
| Need overnight disinfection | Boston Advance Conditioning Solution | Boston Advance kills bacteria; Purilens is not a disinfectant. |
| Convenience and all-in-one care | Boston Advance Conditioning Solution | Boston Advance combines conditioning and disinfection in one solution. |
| Travel-friendly compact option | Purilens Plus Preservative-Free Contact Lens Saline | Purilens 4 oz bottles are TSA-friendly, easy to pack for trips. |
Purilens soothes and rinses without irritation for all-day comfort.
Preservative-free, pH-balanced saline prevents stinging and redness.
per ounce, delivering a 3-month supply for under $20.
Boston Advance conditions and disinfects gas permeable lenses.
Boston Advance kills bacteria; Purilens is not a disinfectant.
Boston Advance combines conditioning and disinfection in one solution.
Purilens 4 oz bottles are TSA-friendly, easy to pack for trips.
What if neither is right?
REFRESH CONTACTS Contact Lens Comfort Drops
$10.79
Extra lubrication for dry eyes during the day — a bestseller for rewetting.
DMV Ultra Contact Lens Remover Tool
$6.99
Gentle, hygienic lens removal — ideal for long nails or scleral lenses.
Frequently Asked Questions
Purilens Plus vs Boston Advance: which is better?
Can I use Boston Advance with soft contact lenses?
Is Purilens Plus safe to use overnight?
How much does a 3-month supply cost?
Why is Purilens preservative-free?
What should I skip in contact lens solutions?
How we compared. We analyzed 16,864 verified Amazon buyer reviews across both brands, watched professional optometrist video reviews from channels like Doctor Eye Health and Dr. EyeGuy, and cross-referenced manufacturer specifications. Prices update weekly from Amazon.
Who wrote this and where's the data from?
Mubboo Editorial Team — independent US-market consumer research. Evaluation based on 16,864+ verified Amazon reviews and manufacturer specifications.